Can I read Ephrin signaling in vivo: Look both ways on EtoBox?

Ephrin signaling in vivo: Look both ways by Alice Davy; Philippe Soriano is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Ephrin signaling in vivo: Look both ways about?

## Abstract Eph receptors and ephrins have captured the interest of the developmental biology community in recent years for their pleiotropic functions during embryogenesis. Loss‐of‐function studies using various animal models have demonstrated the involvement of Ephs and ephrins in many aspects of embryogenesis including segmentation, neural crest cells migration, angiogenesis, and axon guidance. An essential property of this signaling pathway is the ability of both Ephs and ephrins to behave as receptors or ligands and their consequent cell autonomous and nonautonomous mode of action. While many reports did not discriminate between Eph autonomous signaling (forward) and ephrin autonomous signaling (reverse), recent genetic and in vivo studies have shown that both forward and reverse signaling play important roles during embryogenesis. Developmental Dynamics 232:1–10, 2005. © 2004 Wiley‐Liss, Inc.

Who reads Ephrin signaling in vivo: Look both ways?

Author

Alice Davy; Philippe Soriano

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1058-8388)

Published

2004

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)