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Long-term Diet Quality and Its Change in Relation to Late-life Subjective Cognitive Decline by Changzheng Yuan; Yaying Cao; Alberto Ascherio; Olivia I Okereke; Geng Zong; Francine Grodstein; Albert Hofman; Walter C Willett is a Medicine article available to read on EtoBox.

What is Long-term Diet Quality and Its Change in Relation to Late-life Subjective Cognitive Decline about?

## Background: Evidence regarding the role of diet quality, especially its change, in subjective cognitive decline (scd) is scarce. ## Objectives: We aimed to examine associations of long-term diet quality scores, including the alternate mediterranean diet (amed), dietary approaches to stop hypertension (dash), and alternate healthy eating index 2010 (ahei-2010), with scd in the nurses' health study. ## Methods: We followed 49,493 female registered nurses (mean age in 1984: 48 y) from 1984 to 2014. diet scores were derived from 7 repeated ffqs in 1984, 1986, and every 4 y afterward until 2006. self-reported scd was assessed in 2012 and 2014 by a 7-item questionnaire on memory and cognition changes. categorical scd score was classified as "none" (0 points, 40.8%), "moderate" (0.5-2.5 points, 46.9%), and "severe" (3-7 points, 12.3%). ## Results: Multinomial and linear regression models were adjusted for total calorie intake, demographic characteristics, lifestyle, and clinical factors. comparing the top with the bottom quintiles of amed, dash, and ahei-2010, multivariable-adjusted ors (95% cis) for severe scd compared with none were 0.57 (0.51, 0.64), 0.61 (0.55, 0.68), and 0.81 (0.7

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Author

Changzheng Yuan; Yaying Cao; Alberto Ascherio; Olivia I Okereke; Geng Zong; Francine Grodstein; Albert Hofman; Walter C Willett

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Medicine (Health Sciences)