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The Efficacy of Surgical Treatment for the Secondary Prevention of Stroke in Symptomatic Moyamoya Disease by Cong Qian; Xiaobo Yu; Jianru Li; Jingyin Chen; Lin Wang; Gao Chen is a Medicine article available to read on EtoBox.

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## Abstract The treatment of moyamoya disease (MMD) is controversial and often depends on the doctor's experience. In addition, the choice of surgical procedure to treat MMD can differ in many ways. In this study, we performed a meta-analysis to determine whether surgical treatment of MMD is superior to conservative treatment and to provide evidence for the selection of an appropriate surgical treatment. The human case–control studies regarding the association of MMD treatment were systematically identified through online databases (PubMed, Web of Science, Elsevier Science Direct, and Springer Link). Inclusion and exclusion criteria were defined for the eligible studies. The fixed-effects model was performed when homogeneity was indicated. Alternatively, the random-effects model was utilized. This meta-analysis included 16 studies. Surgical treatment significantly reduced the risk of stroke (odds ratio (OR) of 0.17, 95% confidence interval (CI), 0.12–0.26, __P__ < 0.01). A subgroup analysis showed that surgical treatment was more beneficial to hemorrhagic MMD (OR of 0.23, 95% CI, 0.15–0.38, __P__ < 0.01), but there was no significant difference between surgical treatment and conser

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Author

Cong Qian; Xiaobo Yu; Jianru Li; Jingyin Chen; Lin Wang; Gao Chen

Publisher

Lippincott Williams and Wilkins; Elsevier ; Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Elsevier BV; Lippincott Williams & Wilkins Ltd.; Medicine Publishing Company Ltd; Williams & Wilkins; Ovid Technologies (Wolters Kluwer Health) (ISSN 1357-3039)

Published

2015

Language

EN

Field

Medicine (Health Sciences)