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This preprint presents research on the genomic epidemiology of mpox, revealing that the virus emerged in humans around July 2014 in Nigeria, with sustained human-to-human transmission identified since 2017. The study generated 112 MPXV genomes and identified distinct lineages co-circulating during the ongoing epidemic, emphasizing the need for improved pathogen surveillance. The findings highlight the evolutionary dynamics of MPXV, particularly the role of APOBEC3 in increasing the virus

Author

Drogona

Language

EN