Can I read Dehydration, Hemodynamics and Fluid Volume Optimization After Induction of General Anesthesia on EtoBox?

Dehydration, Hemodynamics and Fluid Volume Optimization After Induction of General Anesthesia by Yuhong Li; Rui He; Xiaojiang Ying; Robert G Hahn is a Medicine article available to read on EtoBox.

What is Dehydration, Hemodynamics and Fluid Volume Optimization After Induction of General Anesthesia about?

## OBJECTIVES: Fluid volume optimization guided by stroke volume measurements reduces complications of colorectal and high-risk surgeries. We studied whether dehydration or a strong hemodynamic response to general anesthesia increases the probability of fluid responsiveness before surgery begins. ## METHODS: Cardiac output, stroke volume, central venous pressure and arterial pressures were measured in 111 patients before general anesthesia (baseline), after induction and stepwise after three bolus infusions of 3 ml/kg of 6% hydroxyethyl starch 130/0.4 (n = 86) or Ringer's lactate (n = 25). A subgroup of 30 patients who received starch were preloaded with 500 ml of Ringer's lactate. Blood volume changes were estimated from the hemoglobin concentration and dehydration was estimated from evidence of renal water conservation in urine samples. ## RESULTS: Induction of anesthesia decreased the stroke volume to 62% of baseline (mean); administration of fluids restored this value to 84% (starch) and 68% (Ringer's). The optimized stroke volume index was clustered around 35-40 ml/m^2^/beat. Additional fluid boluses increased the stroke volume by ≥10% (a sign of fluid responsiveness) in patie

Who reads Dehydration, Hemodynamics and Fluid Volume Optimization After Induction of General Anesthesia?

Author

Yuhong Li; Rui He; Xiaojiang Ying; Robert G Hahn

Publisher

Elsevier BV

Published

2015

Language

EN

Field

Medicine (Health Sciences)