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What is Selonsertib in Diabetic Kidney Disease Trial about?
The MOSAIC trial evaluated the efficacy and safety of selonsertib in patients with diabetic kidney disease, showing that it slowed eGFR decline compared to placebo but was associated with a higher incidence of acute kidney injury (AKI) and kidney clinical events. A total of 310 patients were randomized, with results indicating a mean difference in eGFR slopes of 1.20 ml/min per 1.73 m2 per year between the two groups. The study suggests that a larger trial with longer follow-up is needed to better assess th
- Author
- agbox
- Language
- EN