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Dosimetric Comparison Using Different Multileaf Collimeters in Intensity-modulated Radiotherapy for Upper Thoracic Esophageal Cancer by Youling Gong; Shichao Wang; Lin Zhou; Yongmei Liu; Yong Xu; You Lu; Sen Bai; Yuchuan Fu; Qingfeng Xu; Qingfeng Jiang is a Medicine article available to read on EtoBox.
What is Dosimetric Comparison Using Different Multileaf Collimeters in Intensity-modulated Radiotherapy for Upper Thoracic Esophageal Cancer about?
## Abstract ## Purpose To study the impacts of multileaf collimators (MLC) width [standard MLC width of 10 mm (sMLC) and micro-MLC width of 4 mm (mMLC)] in the intensity-modulated radiotherapy (IMRT) planning for the upper thoracic esophageal cancer (UTEC). ## Methods and materials 10 patients with UTEC were retrospectively planned with the sMLC and the mMLC. The monitor unites (MUs) and dose volume histogram-based parameters [conformity index (CI) and homogeneous index (HI)] were compared between the IMRT plans with sMLC and with mMLC. ## Results The IMRT plans with the mMLC were more efficient (average MUs: 703.1 ± 68.3) than plans with the sMLC (average MUs: 833.4 ± 73.8) (__p__ < 0.05). Also, compared to plans with the sMLC, the plans with the mMLC showed advantages in dose coverage of the planning gross tumor volume (Pgtv) (CI 0.706 ± 0.056/HI 1.093 ± 0.021) and the planning target volume (PTV) (CI 0.707 ± 0.029/HI 1.315 ± 0.013) (__p__ < 0.05). In addition, the significant dose sparing in the D~5~ (3260.3 ± 374.0 __vs__ 3404.5 ± 374.4)/gEUD (1815.1 ± 281.7 __vs__ 1849.2 ± 297.6) of the spinal cord, the V~10~ (33.2 ± 6.5 __vs__ 34.0 ± 6.7), V~20~ (16.0 ± 4.6 __vs__ 16.6 ± 4.7)
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- Author
- Youling Gong; Shichao Wang; Lin Zhou; Yongmei Liu; Yong Xu; You Lu; Sen Bai; Yuchuan Fu; Qingfeng Xu; Qingfeng Jiang
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, 2006-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1748-717X)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)