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Respiratory Distress in the Newborn with Primary Ciliary Dyskinesia by Machogu, Evans (author);Gaston, Benjamin (author) is a Medicine article available to read on EtoBox.

What is Respiratory Distress in the Newborn with Primary Ciliary Dyskinesia about?

Primary ciliary dyskinesia (PCD) is inherited in a predominantly autosomal recessive manner with over 45 currently identified causative genes. It is a clinically heterogeneous disorder that results in a chronic wet cough and drainage from the paranasal sinuses, chronic otitis media with hearing impairment as well as male infertility. Approximately 50% of patients have situs inversus totalis. Prior to the development of chronic oto-sino-pulmonary symptoms, neonatal respiratory distress occurs in more than 80% of patients as a result of impaired mucociliary clearance and mucus impaction causing atelectasis and lobar collapse. Diagnosis is often delayed due to overlapping symptoms with other causes of neonatal respiratory distress. A work up for PCD should be initiated in the newborn with compatible clinical features, especially those with respiratory distress, consistent radiographic findings or persistent oxygen requirement and/or organ laterality defects

Who reads Respiratory Distress in the Newborn with Primary Ciliary Dyskinesia?

Author

Machogu, Evans (author);Gaston, Benjamin (author)

Publisher

MDPI AG

Published

2021

Language

EN

Field

Medicine (Health Sciences)