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Laser Balloon Angioplasty Versus Balloon Angioplasty in Normal Rabbit Iliac Arteries by Ronald D. Jenkins; I. Nigel Sinclair; Bradley M. Leonard; Tamas Sandor; Frederick J. Schoen; J. Richard Spears is a Medicine article available to read on EtoBox.

What is Laser Balloon Angioplasty Versus Balloon Angioplasty in Normal Rabbit Iliac Arteries about?

Reduction of vascular recoil is an important goal of laser balloon angioplasty (LBA), wherein Nd:YAG laser radiation is delivered radially during balloon inflation. To define the acute and chronic effects of LBA on the normal arterial lumen in comparison with those of balloon angioplasty (BA), 36 New Zealand White male rabbits (3-4 kg) were subjected to LBA of an external iliac artery and to BA of the contralateral artery with two 1-minute balloon inflations. During LBA, which was performed during the second balloon inflation, either 300 (n = 26) or 176 (n = 10) J were delivered to achieve high and moderate laser doses, respectively, in different LBA groups. Angiography was performed pre-and post-LBNBA and subsequently at intervals of either 1,2,7,28,48, or 223 days. Automated analysis of digitized images was used to measure lumen diameter. No instance of perforation or thrombosis occurred. LBA-treated arteries acutely showed an increase in mean diameter over baseline (+ .5 mm, P<.01) and that of BAtreated arteries ( + .4 mm, P<.Ol). While arteries treated with the high laser dose showed a loss of the initial gain in lumen diameter by 1 month, caused by both extravascular fibrosis

Who reads Laser Balloon Angioplasty Versus Balloon Angioplasty in Normal Rabbit Iliac Arteries?

Author

Ronald D. Jenkins; I. Nigel Sinclair; Bradley M. Leonard; Tamas Sandor; Frederick J. Schoen; J. Richard Spears

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0196-8092)

Published

1989

Language

EN

Field

Medicine (Health Sciences)