Can I read Quantification of myocardial perhsion by MRI after coronary occlusion on EtoBox?

Quantification of myocardial perhsion by MRI after coronary occlusion by Jean‐Paul M. Vallée; H. Dirk Sostman; James R. Macfall; Timothy R. Degrado; Jian Zhang; Laurent Sebbag; Fred R. Cobb; Ted Wheeler; Larry W. Hedlund; Timothy G. Turkington; Charles E. Spritzer; R. Edward Coleman is a Medicine article available to read on EtoBox.

What is Quantification of myocardial perhsion by MRI after coronary occlusion about?

## Abstract The objectives of this study were to define the relationship between the first order constant of Gd‐DTPA transfer (__K__1) and the myocardial blood flow (MBF) at rest and to compare it with an equivalent relationship obtained for positron emission tomography (PET). In a canine model of permanent coronary occlusion (__n__ = 4), myocardial and blood time concentration curves obtained by ^13^N‐ammonia PET and Gd‐DTPA‐enhanced MRI were fitted by a one‐compartment model to determine __K__1. A linear relationship was observed between MRIderived __K__1 and MBF measured by microspheres (__K__1 = 0.88 × flow −0.015, __R =__ 0.95), which compares favorably with the equivalent relationship derived from PET (__K__1 = 0.74 × flow +0.16, __R__ = 0.88). The results of this preliminary study suggest that, at rest and distal to a permanently occluded coronary artery, myocardial perfusion quantification by MRI is possible and can challenge PET.

Who reads Quantification of myocardial perhsion by MRI after coronary occlusion?

Author

Jean‐Paul M. Vallée; H. Dirk Sostman; James R. Macfall; Timothy R. Degrado; Jian Zhang; Laurent Sebbag; Fred R. Cobb; Ted Wheeler; Larry W. Hedlund; Timothy G. Turkington; Charles E. Spritzer; R. Edward Coleman

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)

Published

1998

Language

EN

Field

Medicine (Health Sciences)