About this document
Bioinformatics 2 Practical by chaudhrysariya is a document available to read on EtoBox.
The document outlines a practical exercise for predicting the secondary structure of RNA using Mfold and RNAfold, focusing on the tRNA-Phe from Saccharomyces cerevisiae. It details the principles of thermodynamic energy minimization, practical steps for using Mfold, and comparisons with other methods like RNAfold and RNAalifold. The results indicate that the predicted structures closely match the experimental model, validating the effectiveness of MFE in predicting small RNA structures.
- Author
- chaudhrysariya
- Language
- EN