Can I read Overview of Cardiac Arrhythmias and Treatment Strategies on EtoBox?

Overview of Cardiac Arrhythmias and Treatment Strategies by John Kingma; Chantale Simard; Benoît Drolet is a Medicine article available to read on EtoBox.

What is Overview of Cardiac Arrhythmias and Treatment Strategies about?

Maintenance of normal cardiac rhythm requires coordinated activity of ion channels and transporters that allow well-ordered propagation of electrical impulses across the myocardium. Disruptions in this orderly process provoke cardiac arrhythmias that may be lethal in some patients. Risk of common acquired arrhythmias is increased markedly when structural heart disease caused by myocardial infarction (due to fibrotic scar formation) or left ventricular dysfunction is present. Genetic polymorphisms influence structure or excitability of the myocardial substrate, which increases vulnerability or risk of arrhythmias in patients. Similarly, genetic polymorphisms of drug-metabolizing enzymes give rise to distinct subgroups within the population that affect specific drug biotransformation reactions. Nonetheless, identification of triggers involved in initiation or maintenance of cardiac arrhythmias remains a major challenge. Herein, we provide an overview of knowledge regarding physiopathology of inherited and acquired cardiac arrhythmias along with a summary of treatments (pharmacologic or non-pharmacologic) used to limit their effect on morbidity and potential mortality. Improved unders

Who reads Overview of Cardiac Arrhythmias and Treatment Strategies?

Author

John Kingma; Chantale Simard; Benoît Drolet

Publisher

MDPI AG

Published

2023

Language

EN

Field

Medicine (Life Sciences)