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Gaining Fluid Bed Process Understanding by In-Line Particle Size Analysis by Tero Närvänen; Tanja Lipsanen; Osmo Antikainen; Heikki Räikkönen; Jyrki Heinämäki; Jouko Yliruusi is a Chemistry article available to read on EtoBox.
What is Gaining Fluid Bed Process Understanding by In-Line Particle Size Analysis about?
Different process phenomena and process failure modes could be monitored using the in-line particle size data measured by spatial filtering technique (SFT). In addition to the real-time granule growth monitoring, other events, such as the blocking of filter bags and the distributor plate, could be observed. SFT was used offline, at-line and in-line in 14 differently manufactured granulation batches. No significant fouling occurred during the manufacturing due to the appropriate positioning of the probe. The off-line SFT results correlated well (R 2 1⁄4 0.97) with the sieve analysis results. It was also found that size segregation influenced both the in-line and at-line particle size results during the fluidization: in-line method underestimated and at-line method overestimated the final particle size.
Who reads Gaining Fluid Bed Process Understanding by In-Line Particle Size Analysis?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Tero Närvänen; Tanja Lipsanen; Osmo Antikainen; Heikki Räikkönen; Jyrki Heinämäki; Jouko Yliruusi
- Publisher
- John Wiley and Sons; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 0022-3549)
- Published
- 2009
- Language
- EN
- Field
- Chemistry (Physical Sciences)