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What is SAP2 C. Albicans about?

This study focuses on the design and synthesis of pepstatin analogues as inhibitors of secreted aspartic proteinases (Saps) from Candida albicans, a major fungal pathogen. The research highlights the importance of these proteinases as drug targets due to rising drug resistance and aims to develop selective inhibitors that can enhance treatment efficacy. The synthesized inhibitors demonstrated high potency against specific Sap isoenzymes, providing valuable insights for future anti-virulence drug development

Author

Rahim H

Language

EN