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Controlled underdilation using novel VIATORR® controlled expansion stents improves survival after transjugular intrahepatic portosystemic shunt implantation by Praktiknjo, Michael (author);Abu-Omar, Jasmin (author);Chang, Johannes (author);Thomas, Daniel (author);Jansen, Christian (author);Kupczyk, Patrick (author);Schepis, Filippo (author);Garcia-Pagan, Juan Carlos (author);Merli, Manuela (author);Meyer, Carsten (author);Strassburg, Christian P. (author);Pieper, Claus C. (author);Trebicka, Jonel (author) is a Medicine article available to read on EtoBox.

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## Background & Aims Smaller 8-mm diameter transjugular intrahepatic portosystemic shunts (TIPS) appear to be more beneficial than larger 10-mm TIPS stent-grafts, but lack the ability for secondary dilation in cases of clinical ineffectiveness. Underdilated VIATORR® TIPS stent grafts (VTS) expand passively, whereas novel VIATORR Controlled Expansion (VCX) stent grafts do not. This study evaluated the impact on survival of underdilated VCX compared with VTS in patients with decompensated cirrhosis. ## Methods This was a prospective case-control study including patients with cirrhosis receiving TIPS using 10-mm VCX underdilated to 8 mm. Patients with cirrhosis receiving 10-mm VTS underdilated to 8 mm were matched for age, sex, indication for TIPS, and liver function. ## Results A total of 114 patients (47 VCX, 47 VTS, and 20 fully dilated VCX/VTS) were included. After TIPS implantation, underdilated VCX diameter was 8.0 (7.8–9.2) mm at a median time of 359 (87–450) days, compared with VTS at 9.9 (9.7–10.0) mm (__p__ <0.001). The portosystemic pressure gradient immediately after TIPS procedure and after 7 days did not change significantly in VCX [mean 9.4 (± 0.8) __vs.__ 10.4 (± 0.7)

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Author

Praktiknjo, Michael (author);Abu-Omar, Jasmin (author);Chang, Johannes (author);Thomas, Daniel (author);Jansen, Christian (author);Kupczyk, Patrick (author);Schepis, Filippo (author);Garcia-Pagan, Juan Carlos (author);Merli, Manuela (author);Meyer, Carsten (author);Strassburg, Christian P. (author);Pieper, Claus C. (author);Trebicka, Jonel (author)

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Medicine (Health Sciences)