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What is CLSI AST News: June 2023 Updates about?

This document summarizes updates to CLSI guidelines for aminoglycoside susceptibility breakpoints. It highlights lowered breakpoints for gentamicin, tobramycin, and amikacin against Enterobacterales and Pseudomonas aeruginosa based on pharmacokinetic modeling showing these drugs will only achieve stasis, not killing. The changes are intended to guide appropriate clinical use of aminoglycosides and reduce resistance development.

Author

eletrichuebr

Language

EN