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Can I read Automated Determination of Uric Acid, with Use of a Uricase—Peroxidase System on EtoBox?
Automated Determination of Uric Acid, with Use of a Uricase—Peroxidase System by Gochman, Nathan; Schmitz, Joan M is a Medicine article available to read on EtoBox.
What is Automated Determination of Uric Acid, with Use of a Uricase—Peroxidase System about?
## Abstract An automated colorimetric procedure is described for the determination of serum and urine uric acid with improved specificity. Hydrogen peroxide, formed when uric acid is oxidized by uricase, oxidatively couples with 3-methyl-2-benzothiazolinone hydrazone and N,N-dimethylaniline, in the presence of peroxidase, to produce a stable, sensitive indamine dye. The method is reproducible, and the results correlate well with those obtained by a manual spectrophotometric uricase procedure. Also, the automated procedure is resistant to many added reducing substances that cause positive interferences in alkaline phosphotungstate methods.
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It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Gochman, Nathan; Schmitz, Joan M
- Publisher
- American Association for Clinical Chemistry; American Association for Clinical Chemistry, Inc.; Oxford University Press (OUP); American Association for Clinical Chemistry (AACC); Test accounts (ISSN 0009-9147)
- Published
- 1971
- Language
- EN
- Field
- Medicine (Health Sciences)