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Oprd Epoxide Ros by Bharat Suthar is a document available to read on EtoBox.

The document details the industrial synthesis of the key precursor for the anti-influenza drug Oseltamivir Phosphate, starting from (-)-quinic acid and achieving a yield of 35-38% in seven steps. An alternative method using (-)-shikimic acid was developed, resulting in a higher yield of 63-65% in six steps, with significant improvements in production time and quality. The synthesis process was optimized to reduce unit operations and enhance regioselectivity, making it suitable for large-scale production.

Author

Bharat Suthar

Language

EN