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Can I read Diagnostic accuracy of 99mTc-sestamibi SPECT/CT for detecting renal oncocytomas and other benign renal lesions: a systematic review and meta-analysis on EtoBox?
Diagnostic accuracy of 99mTc-sestamibi SPECT/CT for detecting renal oncocytomas and other benign renal lesions: a systematic review and meta-analysis by Mitchell P. Wilson; Prayash Katlariwala; Mohammad H. Murad; Jonathan Abele; Matthew D. F. McInnes; Gavin Low is a Medicine article available to read on EtoBox.
What is Diagnostic accuracy of 99mTc-sestamibi SPECT/CT for detecting renal oncocytomas and other benign renal lesions: a systematic review and meta-analysis about?
## Purpose: The primary objectives of this systematic review and meta-analysis were to evaluate the diagnostic accuracy of 99mtc-sestamibi spect/ct for detecting renal oncocytoma versus (1) all other renal lesions and (2) chromophobe renal cell carcinoma (chrrcc) alone. ## Methods: A systematic review of medline, embase, scopus, the cochrane library, and the gray literature was performed. original articles with > 5 patients evaluating oncocytomas versus other renal lesions with spect/ct using a pathological reference standard were included. patient, clinical, imaging, and performance parameters were independently acquired by two reviewers. meta-analysis was performed using a bivariate mixed-effects regression model. ## Results: Four articles with a total of 117 renal lesions were included in analysis. the pooled and weighted sensitivity and specificity values of 99mtc-sestamibi spect/ct for detecting (1) renal oncocytoma versus other renal lesions were 92% (95% ci 72-98%) and 88% (95% ci 79-94%), respectively, and (2) 89% and 67%, respectively, for renal oncocytoma versus chrrcc. the specificity for the detecting the oncocytoma-chrrcc spectrum was 96% (95% ci 84-99%). the sensitivi
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- Author
- Mitchell P. Wilson; Prayash Katlariwala; Mohammad H. Murad; Jonathan Abele; Matthew D. F. McInnes; Gavin Low
- Publisher
- Springer Science and Business Media LLC
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)