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Daily Acute Intermittent Hypoxia Combined with Walking Practice Enhances Walking Performance but Not Intralimb Motor Coordination in Persons with Chronic Incomplete Spinal Cord Injury by Andrew Q. Tan; Won Joon Sohn; Avantika Naidu; Randy D. Trumbower is a Neuroscience article available to read on EtoBox.

What is Daily Acute Intermittent Hypoxia Combined with Walking Practice Enhances Walking Performance but Not Intralimb Motor Coordination in Persons with Chronic Incomplete Spinal Cord Injury about?

## Methods: We recruited 11 persons with chronic (> 1 year), incomplete sci to participate in a randomized, double-blind, balanced, crossover study. participants first received either daily (5 consecutive days) aih (15, 90-s episodes of 10.0% o with 60s intervals at 20.9% o) or sham (15, 90s episodes at 20.9% o with 60s intervals at 20.9% o) followed by 30-min of overground walking practice. they received the second treatment after a minimum 2-week washout period. we quantified overground walking performance, in terms of speed and endurance, using the 10-meter walk test (10mwt) and 6-minute walk test (6mwt), respectively. we quantified intralimb motor coordination using kinematic variability measures of foot trajectory (i.e., endpoint variability, ev) and of inter-joint coupling between the hip and knee, as well as between the knee and ankle joints (i.e., angular coefficient of correspondence, acc). we compared the changes in walking performance relative to baseline (bl) between daily aih + walk and daily sham+walk on treatment day 5 (t), 1-week follow-up (f), and 2-weeks follow-up (f). we also compared these changes between participants who used bilateral walking aids (n = 5) and

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Author

Andrew Q. Tan; Won Joon Sohn; Avantika Naidu; Randy D. Trumbower

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Neuroscience (Life Sciences)