Can I read Platelet-activating factor (PAF) receptor binding antagonists from Alpinia officinarum on EtoBox?
Platelet-activating factor (PAF) receptor binding antagonists from Alpinia officinarum by Gao-jun Fan; Young-Hwa Kang; Yong Nam Han; Byung Hoon Han is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Platelet-activating factor (PAF) receptor binding antagonists from Alpinia officinarum about?
The bioassay-guided purification of ether extracts of Alpinia officinarum led to the isolation of two new compounds 6hydroxy-1,7-diphenyl-4-en-3-heptanone (1) and 6-(2-hydroxy-phenyl)-4-methoxy-2-pyrone (4) as well as three known compounds 1,7-diphenyl-4-en-3-heptanone (2), 1,7-diphenyl-5-methoxy-3-heptanone (3), and apigenin (5). Their structures were established on the basis of spectral methods. All three diarylheptanoids 1, 2, and 3 exhibited potent PAF receptor binding inhibitory activities with an IC 50 of 1.3, 5.0, and 1.6 lM, respectively. These studies have identified diarylheptanoids as a novel class of potent PAF antagonists.
Who reads Platelet-activating factor (PAF) receptor binding antagonists from Alpinia officinarum?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Gao-jun Fan; Young-Hwa Kang; Yong Nam Han; Byung Hoon Han
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2007
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)