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Can I read Influence of Cardiac Remodeling on Clinical Outcomes in Patients With Aortic Regurgitation on EtoBox?
Influence of Cardiac Remodeling on Clinical Outcomes in Patients With Aortic Regurgitation by Maan Malahfji; Valentina Crudo; Yodying Kaolawanich; Duc T. Nguyen; Amr Telmesani; Mujtaba Saeed; Michael J. Reardon; William A. Zoghbi; Venkateshwar Polsani; Michael Elliott; Robert O. Bonow; Edward A. Graviss; Raymond Kim; Dipan J. Shah is a Medicine article available to read on EtoBox.
What is Influence of Cardiac Remodeling on Clinical Outcomes in Patients With Aortic Regurgitation about?
Background Quantitative cardiac magnetic resonance (CMR) outcome studies in aortic regurgitation (AR) are few. It is unclear if volume measurements are beneficial over diameters. Objectives This study sought to evaluate the association of CMR quantitative thresholds and outcomes in AR patients. Methods In a multicenter study, asymptomatic patients with moderate or severe AR on CMR with preserved left ventricular ejection fraction (LVEF) were evaluated. Primary outcome was development of symptoms or decrease in LVEF to <50%, development of guideline indications for surgery based on LV dimensions, or death under medical management. Secondary outcome was the same as the primary outcome, excluding surgery for remodeling indications. We excluded patients who underwent surgery within 30 days of CMR. Receiver-operating characteristic analyses for the association with outcomes were performed. Results We studied 458 patients (median age: 60 years; IQR: 46-70 years). During a median follow-up of 2.4 years (IQR: 0.9-5.3 years), 133 events occurred. Optimal thresholds were regurgitant volume of 47 mL and regurgitant fraction of 43%, indexed LV end-systolic (iLVES) volume of 43 mL/m2, indexed L
Who reads Influence of Cardiac Remodeling on Clinical Outcomes in Patients With Aortic Regurgitation?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Maan Malahfji; Valentina Crudo; Yodying Kaolawanich; Duc T. Nguyen; Amr Telmesani; Mujtaba Saeed; Michael J. Reardon; William A. Zoghbi; Venkateshwar Polsani; Michael Elliott; Robert O. Bonow; Edward A. Graviss; Raymond Kim; Dipan J. Shah
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)