Opening book details…
Can I read Fate of the Capping Agent of Biologically Produced Gold Nanoparticles and Adsorption of Enzymes Onto Their Surface on EtoBox?
Fate of the Capping Agent of Biologically Produced Gold Nanoparticles and Adsorption of Enzymes Onto Their Surface by Pourali, Parastoo (author);Dzmitruk, Volha (author);Pátek, Miroslav (author);Neuhöferová, Eva (author);Svoboda, Milan (author);Benson, Veronika (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Fate of the Capping Agent of Biologically Produced Gold Nanoparticles and Adsorption of Enzymes Onto Their Surface about?
Enzymotherapy based on DNase I or RNase A has often been suggested as an optional strategy for cancer treatment. The efficacy of such procedures is limited e.g. by a short half-time of the enzymes or a low rate of their internalization. The use of nanoparticles, such as gold nanoparticles (AuNPs), helps to overcome these limits. Specifically, biologically produced AuNPs represent an interesting variant here due to naturally occurring capping agents (CA) on their surface. The composition of the CA depends on the producing microorganism. CAs are responsible for the stabilization of the nanoparticles, and promote the direct linking of targeting and therapeutic molecules. This study provided proof of enzyme adsorption onto gold nanoparticles and digestion efficacy of AuNPs-adsorbed enzymes. We employed __Fusarium oxysporum__ extract to produce AuNPs. These nanoparticles were round or polygonal with a size of about 5 nm, negative surface charge of about − 33 mV, and maximum absorption peak at 530 nm. After the adsorption of DNAse I, RNase A, or Proteinase K onto the AuNPs surface, the nanoparticles exhibited shifts in surface charge (values between − 22 and − 13 mV) and maximum absorpti
Who reads Fate of the Capping Agent of Biologically Produced Gold Nanoparticles and Adsorption of Enzymes Onto Their Surface?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Pourali, Parastoo (author);Dzmitruk, Volha (author);Pátek, Miroslav (author);Neuhöferová, Eva (author);Svoboda, Milan (author);Benson, Veronika (author)
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)