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Antimicrobial susceptibility profiles of aerobic and facultative Gram-negative bacilli isolated from patients with intra-abdominal infections in the Asia-Pacific region according to currently established susceptibility interpretive criteria by Yen-Hsu Chen; Po-Ren Hsueh; Robert E. Badal; Stephen P. Hawser; Daryl J. Hoban; Samuel K. Bouchillon; Yuxing Ni; David L. Paterson is a Medicine article available to read on EtoBox.

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Journal of Infection (2011) 62, 280e291 Carbapenems; Interpretive susceptibility criteria Results: Enterobacteriaceae comprised 89.5% of the isolates of which Escherichia coli was the most common species (56.7%). Enterobacteriaceae showed poor susceptibility to ampicillinsulbactam in China (25.3%) and India (19%), and to fluoroquinolones in India (23.4%) and China (37.7%). The rates of extended-spectrum b-lactamase (ESBL)-producing E. coli (36.8%) and Klebsiella pneumoniae (26.3%) remained high. The resistance of ESBL-producing K. pneumoniae to carbapenems also increased, especially to ertapenem (9.9%). Using M100-S20 criteria, 19% of ESBL-producing E. coli and 9% of ESBL-producing K. pneumoniae were susceptible to ceftazidime; 5% and 10% were susceptible to cefepime, respectively. Using M100-S20-U guidelines, the susceptibility rates of ESBL-producing K. pneumoniae (88%) and Enterobacter cloacae (69%) to ertapenem were substantially decreased from those determined using M100-S20. Conclusions: These up-to-date epidemiology and antimicrobial resistance surveillance data are crucial to select appropriate treatment of IAIs.

Who reads Antimicrobial susceptibility profiles of aerobic and facultative Gram-negative bacilli isolated from patients with intra-abdominal infections in the Asia-Pacific region according to currently established susceptibility interpretive criteria?

Author

Yen-Hsu Chen; Po-Ren Hsueh; Robert E. Badal; Stephen P. Hawser; Daryl J. Hoban; Samuel K. Bouchillon; Yuxing Ni; David L. Paterson

Publisher

Elsevier Science; Elsevier ; W. B. Saunders Co., Ltd.; Elsevier BV (ISSN 0163-4453)

Published

2011

Language

EN

Field

Medicine (Health Sciences)