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HPLC-UV Method for Atorvastatin Bioequivalence by nurdinahmad.st is a document available to read on EtoBox.
A high-performance liquid chromatographic-ultraviolet (HPLC-UV) method was developed and validated for the bioequivalence study of atorvastatin in human plasma, achieving an average recovery of 98.7%. The method was applied in a randomized, cross-over study comparing two atorvastatin tablet preparations, Lipitor and Lipirex, in twelve healthy male volunteers, showing comparable pharmacokinetic parameters. The study concluded that both formulations can be regarded as bioequivalent based on their pharmacokine
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- nurdinahmad.st
- Language
- EN