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Prognostic Value of Preoperative Magnetic Resonance Imaging of the Pelvis in Rectal Cancer by A. Martling; T. Holm; S. Bremmer; J. Lindholm; B. Cedermark; L. Blomqvist is a Medicine article available to read on EtoBox.

What is Prognostic Value of Preoperative Magnetic Resonance Imaging of the Pelvis in Rectal Cancer about?

## Abstract ## Background Despite radiotherapy and improved surgical techniques, local recurrence rates after treatment of rectal cancer still vary between 3 and 30 per cent. Tumour involvement of the circumferential resection margin (CRM) predicts a high risk of local recurrence. Magnetic resonance imaging (MRI) allows accurate description of the tumour and its spread within the mesorectum. The aim of this study was to assess the prognostic impact of an involved CRM identified at preoperative MRI in patients with rectal cancer. ## Methods Preoperative MRI was performed in 115 patients with rectal cancer between 1995 and 1999. The images were evaluated retrospectively. The shortest distance from the tumour to the CRM was measured, correlated with patient outcome and compared with histopathological findings. ## Results The risk of any recurrence in patients with or without a tumour-involved margin on MRI was nine of 29 and nine of 57 respectively (P = 0·036). Overall survival at 5 years was 43 and 77 per cent (P = 0·012) respectively. Twenty-four of 30 patients who had an involved CRM on histopathology were correctly identified by MRI. ## Conclusion Patients with a potentially invol

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Author

A. Martling; T. Holm; S. Bremmer; J. Lindholm; B. Cedermark; L. Blomqvist

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Oxford University Press (OUP) (ISSN 0007-1323)

Published

2003

Language

EN

Field

Medicine (Health Sciences)