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Can I read Antiepileptic Drug-induced Severe Granulomatous Interstitial Nephritis on EtoBox?
Antiepileptic Drug-induced Severe Granulomatous Interstitial Nephritis by Aggarwal, Sunita (author);Garg, Chetan (author);Kumar, Shanu (author);Singh, Ranvijay (author) is a Medicine article available to read on EtoBox.
What is Antiepileptic Drug-induced Severe Granulomatous Interstitial Nephritis about?
Granulomatous interstitial nephritis (GIN) is a type of tubulointerstitial nephritis characterised by tubulointerstitial infiltration of mononuclear cells and eosinophils. It accounts for about 6% of all tubulointerstitial nephritis and is detected in ∼0.5%–0.9% of all renal biopsies. GIN has been linked to several antibiotics, non steroidal anti-inflammatory drugs (NSAIDs), and granulomatous disorders like tuberculosis and sarcoidosis but is rarely reported with anti-epileptic medications like phenytoin and levetiracetam. We present a case report of a man in his early 20’s with previously normal renal function who developed GIN following levetiracetam and phenytoin consumption for 7 years. After withdrawal of the causative drug and starting steroid therapy, his kidney function gradually improved. In cases of GIN, medication history is important in the evaluation of aetiology.
Who reads Antiepileptic Drug-induced Severe Granulomatous Interstitial Nephritis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Aggarwal, Sunita (author);Garg, Chetan (author);Kumar, Shanu (author);Singh, Ranvijay (author)
- Publisher
- BMJ
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)