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Correlation of computerized gray-scale sonographic findings with thyroid function and thyroid autoimmune activity in patients with Hashimoto's thyroiditis by Maurizio Loy; Maria Elisabetta Cianchetti; Francescopaolo Cardia; Alessandro Melis; Francesco Boi; Stefano Mariotti is a Medicine article available to read on EtoBox.
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## Abstract ## Purpose The objective of this study was to retrospectively assess whether computerized gray‐scale sonography can allow objective measurement of thyroid echogenicity in patients with Hashimoto's thyroiditis (HT) at various functional stages of the disease. ## Methods Of the 77 patients with HT who were included in our study, 28 had been euthyroid, 20 had had subclinical hypothyroidism, and 29 had had clinical hypothyroidism. Of those with clinical hypothyroidism, 6 had been untreated and 23 had been receiving L‐thyroxine substitution therapy. Fifty volunteers without thyroid disease served as a control group. Thyroid echogenicity was evaluated by computerized gray‐scale sonography as mean tissue density (MTD) ± standard deviation; the echogenicity of the prethyroid muscles served as a control of the system variability. ## Results The MTD was significantly lower for the patients with HT (15.9 ± 4) than for the control subjects (24.3 ± 3; __p__ < 0.05). Moreover, a significant difference was found between the MTD values of euthyroid patients with HT (18.9 ± 3.4) and hypothyroid patients with HT analyzed either as a group (14.3 ± 3.8) or separately for subclinical hypoth
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- Author
- Maurizio Loy; Maria Elisabetta Cianchetti; Francescopaolo Cardia; Alessandro Melis; Francesco Boi; Stefano Mariotti
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0091-2751)
- Published
- 2004
- Language
- EN
- Field
- Medicine (Health Sciences)