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Liposomal Irinotecan A Review in Metastatic Pancreatic Adenocarcinoma 2020 by ljlj66 is a document available to read on EtoBox.
Liposomal irinotecan (nal-IRI) is an innovative treatment for metastatic pancreatic ductal adenocarcinoma (mPDAC) that improves survival outcomes when combined with 5-fluorouracil and leucovorin in patients previously treated with gemcitabine. The NAPOLI-1 trial demonstrated a significant median overall survival advantage of approximately two months for nal-IRI plus 5-FU/LV compared to 5-FU/LV alone, with a manageable safety profile. Real-world studies further support the efficacy and safety of this combina
- Author
- ljlj66
- Language
- EN