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Bi-spectral Index-guided Comparison of Propofol Versus Etomidate for Induction in Electroconvulsive Therapy by Kumari, Kamlesh (author);Rajpurohit, Vikas (author);Chaudhary, Kriti (author);Kishan, Rama (author);Sethi, Priyanka (author);Sharma, Ankur (author) is a Medicine article available to read on EtoBox.

What is Bi-spectral Index-guided Comparison of Propofol Versus Etomidate for Induction in Electroconvulsive Therapy about?

## Background: Previous studies have compared varying doses of propofol and etomidate for electroconvulsive therapy (ECT) without monitoring the depth of anesthesia. Seizure duration may vary with the depth of anesthesia. ## Aim: This study aimed to compare the effects of bi-spectral index (BIS)-guided induction with propofol and etomidate on various parameters of ECT. ## Settings and Design: This was a prospective, randomized, double-blind study. ## Materials and Methods: Sixty patients undergoing ECT were randomly allocated to two groups. Group P received intravenous propofol 1–2 mg.kg ^−1^ and Group E received etomidate 0.1–0.3 mg.kg ^−1^ to attain a BIS of 40–60. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and BIS were recorded at various time points intraoperatively till 30 min following ECT. Seizure duration, recovery time, and adverse effects were also recorded. ## Statistical Analysis: Quantitative data were compared using unpaired __t__-test. Chi-square test or Fisher's exact test was used to compare categorical data. __P__ < 0.05 was considered statistically significant. ## Results: The mean induction time and seizure duration were shor

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Author
Kumari, Kamlesh (author);Rajpurohit, Vikas (author);Chaudhary, Kriti (author);Kishan, Rama (author);Sethi, Priyanka (author);Sharma, Ankur (author)
Publisher
Medknow
Published
2020
Language
EN
Field
Medicine (Health Sciences)

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