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What is Domperidone Gastro-Retentive Beads Development about?
The study focuses on the development and evaluation of gastro-retentive drug delivery systems using domperidone/Dowex resinate complex embedded in buoyant alginate beads and emulgel formulations. Two techniques were employed to enhance buoyancy: incorporating NaHCO3 for effervescence and adding light mineral oil for low-density emulgel beads. The optimized formulation demonstrated effective drug release control, prolonged floating duration, and stability, suggesting potential for improved bioavailability an
- Author
- Lina Winarti
- Language
- EN