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Ascorbic acid ## Acute kidney injury and oxalate nephropathy: case report A 70-year-old woman developed oxalate nephropathy and acute kidney injury while receiving treatment with ascorbic acid for septic shock [time to reactions onset not stated]. The woman, who had a history of end stage renal disease due to autosomal dominant polycystic kidney disease, underwent dual deceased donor kidney transplantation. On posttransplant day 9, she developed septic shock from pneumonia. Therefore, she started receiving empiric treatment with IV ascorbic acid 1.5g every 6 hours, thiamine and unspecified antibacterials, vasopressors and stress dose steroids. She received ascorbic acid for 5 days (6g/day). During hospitalisation, she developed another septic shock due to intraabdominal abscess and secondary peritonitis. Therefore, she was treated again with IV ascorbic acid 6 g/day for 5 days. Her ICU stay was prolonged and complicated by respiratory failure and two episodes of septic shocks. Additionally, she developed stage 3 acute kidney injury. The woman underwent haemodialysis. Progressively, her clinical condition improved, but without any signs of allograft recovery at 2 months of posttrans

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Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)