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Lack Of Benefit Of Increasing Radiation Dose Beyond Conventional Doses In Patients Receiving Neoadjuvant Chemoradiation For Rectal Cancer by A.G. Abraham; K.J. Joseph; J. Thai; S. Ghosh; W. Cheung; Y. Xu; D.M. Severin; K. Tankel; T. Nijjar; N.H. Usmani is a Medicine article available to read on EtoBox.
What is Lack Of Benefit Of Increasing Radiation Dose Beyond Conventional Doses In Patients Receiving Neoadjuvant Chemoradiation For Rectal Cancer about?
Purpose/Objective(s): The study was to investigate recurrence patterns of thoracic esophageal squamous cell carcinoma (ESCC) after radical surgery and its implication in the clinical target volume (CTV) designed of postoperative radiotherapy (PORT) in patients with ESCC. Materials/Methods: A total of 431 recurrent ESCC patients after radical surgery between 2014 and 2018 were included in this study. Recurrence patterns, especially anastomotic and regional lymph node recurrences, were analyzed. A T-shaped CTV were proposed for PORT and were evaluated whether it could cover most of regional lymph node recurrences. Results: These patients all experienced anastomotic and/or regional lymph node recurrences. Among the 431 patients, 28 cases (6.5%) had anastomotic recurrence, 208 cases (48.3%) had lymph node recurrence. Those sites with LNM rate higher than 15% in Upper thoracic ESCC were as follows: No.101, No.104R, No.104L, No.106recR, No.106recL, No.106pre, No.106tb, No.107, No. 109; those in Middle thoracic ESCC were as follows: No.104R, No.104L, 106recR, No.106recL, No.106pre, No.106tb, No.107; and those in lower thoracic ESCC were as follows: No.104L, 106recR, No.106recL, No. 106pre
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- Author
- A.G. Abraham; K.J. Joseph; J. Thai; S. Ghosh; W. Cheung; Y. Xu; D.M. Severin; K. Tankel; T. Nijjar; N.H. Usmani
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)