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What is Nanobody Nb16 for Peanut Allergen Detection about?

This study focuses on developing a nanobody specific to the peanut major allergen Ara h 3, which is crucial for food safety due to the prevalence of peanut allergies. A library of nanobodies was constructed and screened, resulting in the identification of Nb16, which binds to Ara h 3 with a dissociation constant of 400 nM. The structural analysis of the Ara h 3-Nb16 complex provides insights into the allergenicity of Ara h 3 and suggests potential applications for Nb16 in biosensor development for allergen

Author

Abdus Samad

Language

EN