Can I read TWEAK/Fn14 in Bullous Pemphigoid Pathogenesis on EtoBox?

TWEAK/Fn14 in Bullous Pemphigoid Pathogenesis by fertynmoi9 is a document available to read on EtoBox.

What is TWEAK/Fn14 in Bullous Pemphigoid Pathogenesis about?

The study investigates the role of TWEAK in the pathogenesis of bullous pemphigoid (BP), finding elevated serum TWEAK levels and a positive correlation with anti-BP180 antibodies in patients. TWEAK activation reduces BP180 expression and cellular adherence in keratinocytes through the activation of NF-kB and ERK pathways, with ADAM17 playing a significant role in this process. The findings suggest that TWEAK may serve as a biomarker or therapeutic target for BP.

Author

fertynmoi9

Language

EN