About this document
Gene Delivery Into The Central Nervous System (CNS) Using AAV Vectors by Ankan Mondal is a document available to read on EtoBox.
This chapter discusses the use of adeno-associated virus (AAV) vectors for gene delivery to the central nervous system (CNS) to treat neurological disorders, emphasizing the challenges posed by the blood-brain barrier (BBB). It outlines various strategies for gene transfer, including brain-directed local injections and systemic administration, particularly during the neonatal period when the BBB is more permeable. The chapter highlights the advantages of AAV vectors, such as their safety and ability to tran
- Author
- Ankan Mondal
- Language
- EN