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Thymic carcinoma. A distinct clinical entity responsive to chemotherapy by Lamont G. Weide; Thomas M. Ulbright; Patrick J. Loehrer Sr.; Stephen D. Williams is a Medicine article available to read on EtoBox.

What is Thymic carcinoma. A distinct clinical entity responsive to chemotherapy about?

Background. Thymic carcinomas are rare tumors of the anterior mediastinum. These tumors are distinct thymic neoplasms that differ from their more common counterpart, thymoma. As opposed to thymomas, thymic carcinomas are histologically malignant neoplasms with a clinical course that tends to be much more aggressive than that of patients with thymoma. Between 1984 and 1990, five patients with thymic carcinoma treated with cisplatin-based combination chemotherapy were seen at Indiana University Hos- pital. These patients' diagnoses, courses, and treatments were reviewed. Results. Three patients responded (two completely) to cisplatin-based chemotherapy. Conclusions. This form of chemotherapy merits additional study in such patients, and our experience indicates that at least some will have clinically meaningful responses. The optimum regimen is unclear, but would contain cisplatin and probably should be similar to that used in germ cell tumors.

Who reads Thymic carcinoma. A distinct clinical entity responsive to chemotherapy?

Author

Lamont G. Weide; Thomas M. Ulbright; Patrick J. Loehrer Sr.; Stephen D. Williams

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1993

Language

EN

Field

Medicine (Health Sciences)