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Effect of a Hypocaloric Diet in Transaminases in Nonalcoholic Fatty Liver Disease and Obese Patients, Relation with Insulin Resistance by D.A. de Luis; R. Aller; O. Izaola; M. Gonzalez Sagrado; R. Conde; J.M. Gonzalez is a Medicine article available to read on EtoBox.

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## Objective: The aim of our study was to examine the changes in hypertransaminasemia after weight reduction in obese patients with and without nonalcoholic fatty liver disease (nafld) and the relation with insulin resistance. ## Research methods: A population of 142 obesity nondiabetic was treated with a hypocaloric diet (1520 kcal) during 3 months. patients were classified as group i (control, n=112) when serum (alanine aminotransferase) alt activity was normal or group ii (nafld, n=30) when serum alt activity was greater than the upper limit of normal reference laboratory (>or=43 ui/l). ## Results: In control group, body mass index (bmi) (35.3+/-5.6 vs. 33.5+/-5.5: p<0.05), weight (89.6+/-17.2 kg vs. 85.6+/-16.5 kg: p<0.05) and insulin (15+/-7.9 mui/l vs. 13.1+/-7.4 mui/l: p<0.05) levels decreased. in nafld group, bmi (37.1+/-4.2 vs. 35.1+/-4.6: p<0.05), weight (101+/-22 kg vs. 96.4+/-11.6 kg: p<0.05), insulin (26.8+/-8.9 mui/l vs. 12.7+/-8.4 mui/l: p<0.05) and homa (3.1+/-1.6 vs. 1.9+/-1.7: p<0.05) decreased. liver function improved in both groups (alt; group i 19.9+/-4.6 ui/l vs. 18.3+/-3.9 ui/l: p<0.05 and group ii 37.8+/-4.2 ui/l vs. 27.1+/-7.8 ui/l: p<0.05), (aspartate amin

Who reads Effect of a Hypocaloric Diet in Transaminases in Nonalcoholic Fatty Liver Disease and Obese Patients, Relation with Insulin Resistance?

Author

D.A. de Luis; R. Aller; O. Izaola; M. Gonzalez Sagrado; R. Conde; J.M. Gonzalez

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0168-8227)

Published

2008

Language

EN

Field

Medicine (Health Sciences)