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Synthesis of 5‐Cyanopyrazolo[3,4‐ B ]Pyridines in the Reaction of 5‐Amino‐3‐methyl‐1‐phenylpyrazole with Arylidene Derivatives of Malonodinitrile and Ethyl Cyanoacetate by Jairo Quiroga; Mario Alvarado; Braulio Insuasty; Rodolfo Moreno; Enrique Raviña; Isabel Estevez; Regina H. De Almeida S. is a Chemistry article available to read on EtoBox.
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## Abstract This paper describes the synthesis of a new series of 6‐amino‐4‐aryl‐5‐cyanopyrazolo[3,4‐__b__]pyridines 4 and 4‐aryl‐5‐cyano‐6__H__‐pyrazolo[3,4‐__b__]pyridin‐6‐ones 5 from the reaction of 5‐amino‐3‐methyl‐1‐phenylpyrazole 1 with arylidene derivatives of malonodinitrile 2 and ethyl cyanoacetate 3. The structure of the final compounds was determined on the basis of nmr measurements, especially by ^1^H, ^1^H‐, ^1^H, ^13^C‐COSY, DEPT and X‐ray diffraction.
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- Author
- Jairo Quiroga; Mario Alvarado; Braulio Insuasty; Rodolfo Moreno; Enrique Raviña; Isabel Estevez; Regina H. De Almeida S.
- Publisher
- Journal of Heterocyclic Chemistry; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley; FASEB (ISSN 0022-152X)
- Published
- 1999
- Language
- EN
- Field
- Chemistry (Physical Sciences)