Opening book details…
Can I read Four-point Impedance as a Biomarker for Bleeding During Cochlear Implantation on EtoBox?
Four-point Impedance as a Biomarker for Bleeding During Cochlear Implantation by Bester, Christofer; Razmovski, Tayla; Collins, Aaron; Mejia, Olivia; Foghsgaard, SÃ ̧ren; Mitchell-Innes, Alistair; Shaul, Chanan; Campbell, Luke; Eastwood, Hayden; OâLeary, Stephen is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Four-point Impedance as a Biomarker for Bleeding During Cochlear Implantation about?
Cochlear implantation has successfully restored the perception of hearing for nearly 200 thousand profoundly deaf adults and children. More recently, implant candidature has expanded to include those with considerable natural hearing which, when preserved, provides an improved hearing experience in noisy environments. But more than half of these patients lose this natural hearing soon after implantation. To reduce this burden, biosensing technologies are emerging that provide feedback on the quality of surgery. Here we report clinical findings on a new intra-operative measurement of electrical impedance (4-point impedance) which, when elevated, is associated with high rates of post-operative hearing loss and vestibular dysfunction. __In vivo__ and __in vitro__ data presented suggest that elevated 4-point impedance is likely due to the presence of blood within the cochlea rather than its geometry. Four-point impedance is a new marker for the detection of cochlear injury causing bleeding, that may be incorporated into intraoperative monitoring protocols during CI surgery.
Who reads Four-point Impedance as a Biomarker for Bleeding During Cochlear Implantation?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Bester, Christofer; Razmovski, Tayla; Collins, Aaron; Mejia, Olivia; Foghsgaard, SÃ ̧ren; Mitchell-Innes, Alistair; Shaul, Chanan; Campbell, Luke; Eastwood, Hayden; OâLeary, Stephen
- Publisher
- Springer Science and Business Media LLC; London: Nature Publishing Group; [London]: Springer Nature; Nature Publishing Group; Society for Mining, Metallurgy and Exploration Inc.; Research Square; Springer Nature; Island Press (ISSN 2045-2322)
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)