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Nerylneryl diphosphate is the precursor of serrulatane, viscidane and cembrane-type diterpenoids in Eremophila species by Gericke, Oliver; Hansen, Nikolaj Lervad; Pedersen, Gustav Blichfeldt; Kjaerulff, Louise; Luo, Dan; Staerk, Dan; MÃ ̧ller, Birger Lindberg; Pateraki, Irini; Heskes, Allison Maree is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Nerylneryl diphosphate is the precursor of serrulatane, viscidane and cembrane-type diterpenoids in Eremophila species about?
## Background __Eremophila__ R.Br. (Scrophulariaceae) is a diverse genus of plants with species distributed across semi-arid and arid Australia. It is an ecologically important genus that also holds cultural significance for many Indigenous Australians who traditionally use several species as sources of medicines. Structurally unusual diterpenoids, particularly serrulatane and viscidane-types, feature prominently in the chemical profile of many species and recent studies indicate that these compounds are responsible for much of the reported bioactivity. We have investigated the biosynthesis of diterpenoids in three species: __Eremophila lucida__, __Eremophila drummondii__ and __Eremophila denticulata__ subsp. __trisulcata__. ## Results In all studied species diterpenoids were localised to the leaf surface and associated with the occurrence of glandular trichomes. Trichome-enriched transcriptome databases were generated and mined for candidate terpene synthases (TPS). Four TPSs with diterpene biosynthesis activity were identified: __El__TPS31 and __El__TPS3 from __E. lucida__ were found to produce (3__Z__,7__Z__,11__Z__)-cembratrien-15-ol and 5-hydroxyviscidane, respectively, and __
Who reads Nerylneryl diphosphate is the precursor of serrulatane, viscidane and cembrane-type diterpenoids in Eremophila species?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Gericke, Oliver; Hansen, Nikolaj Lervad; Pedersen, Gustav Blichfeldt; Kjaerulff, Louise; Luo, Dan; Staerk, Dan; MÃ ̧ller, Birger Lindberg; Pateraki, Irini; Heskes, Allison Maree
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2229)
- Published
- 2020
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)