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What is Carbapenem Neurotoxicity Review about?

Carbapenems, a class of beta-lactam antibiotics, have a higher neurotoxic potential compared to penicillins and cephalosporins, with imipenem/cilastatin being particularly associated with seizures due to excessive dosages. The neurotoxicity is linked to interactions with GABA receptors, and the structural characteristics of carbapenems, especially the C-2 side chain, play a significant role in inducing convulsions. While some carbapenems exhibit lower neurotoxicity and can be safely used at higher doses, th

Author

Raeesudheen

Language

EN