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Desloratadine is a nonsedating antihistamine used to treat seasonal allergic rhinitis and chronic idiopathic urticaria in patients over 12 years old. It works by competitively blocking the effects of histamine at peripheral H1 receptor sites. Common side effects include somnolence, dry mouth, and fatigue. Nurses should assess for allergies to desloratadine or related drugs, hepatic or renal impairment, pregnancy, or lactation. Patients should take it as prescribed and report any difficulty breathing or othe

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