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Protein Deimination in Human Health and Disease by Anthony P. Nicholas; Sanjoy K. Bhattacharya; Paul R. Thompson is a nonfiction available to read on EtoBox.

What is Protein Deimination in Human Health and Disease about?

Published in 2014, Protein Deimination in Human Health and Disease was the first book on this novel post-translational modification, in which selected positively-charged arginine amino acids are converted to neutral citrulline amino acids by the peptidyl-arginine deiminase (PAD) family of enzymes. This area of research continues to expand rapidly, necessitating the need for this second edition. Chronicling the latest inflammatory, epigenetic, neurodegenerative, and carcinogenic processes, Protein Deimination in Human Health and Disease, Second Edition, updates the latest advances in deimination research, including new information on PAD enzyme structure and activity, and how PAD knock-out animals are being used to study known and newly-discovered links to various human diseases. The first edition outlined what was known about citrullinated proteins in normal tissues such as skin and hair, as well as in maladies such as rheumatoid arthritis (RA), multiple sclerosis (MS), Alzheimer's disease (AD), glaucoma, peripheral nerve injury, neonatal hypoxic brain damage, and breast cancer. This second edition addresses numerous additional disorders such as diabetes, asthma, traumatic brain in

Who reads Protein Deimination in Human Health and Disease?

Author

Anthony P. Nicholas; Sanjoy K. Bhattacharya; Paul R. Thompson

Publisher

Springer International Publishing : Imprint : Springer

Published

2017

Language

EN

ISBN

9783319582436

Category

nonfiction

Subjects

Science, Chemistry, Medical