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Brown/Beige adipose tissues and the emerging role of their secretory factors in improving metabolic health: The batokines by Bilal Ahmad; Muhammad Sufyan Vohra; Mansab Ali Saleemi; Christopher J. Serpell; Isabel Lim Fong; Eng Hwa Wong is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Brown/Beige adipose tissues and the emerging role of their secretory factors in improving metabolic health: The batokines about?
Brown and beige adipose tissues are the primary sites for adaptive non-shivering thermogenesis. Although they have been known principally for their thermogenic effects, in recent years, it has emerged that, just like white adipose tissue (WAT), brown and beige adipose tissues also play an important role in the regulation of metabolic health through secretion of various brown adipokines (batokines) in response to various physiological cues. These secreted batokines target distant organs and tissues such as the liver, heart, skeletal muscles, brain, WAT, and perform various local and systemic functions in an autocrine, paracrine, or endocrine manner. Brown and beige adipose tissues are therefore now receiving increasing levels of attention with respect to their effects on various other organs and tissues. Identification of novel secreted factors by these tissues may help in the discovery of drug candidates for the treatment of various metabolic disorders such as obesity, type-2 diabetes, skeletal deformities, cardiovascular diseases, dyslipidemia. In this review, we comprehensively describe the emerging secretory role of brown/beige adipose tissues and the metabolic effects of variou
Who reads Brown/Beige adipose tissues and the emerging role of their secretory factors in improving metabolic health: The batokines?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Bilal Ahmad; Muhammad Sufyan Vohra; Mansab Ali Saleemi; Christopher J. Serpell; Isabel Lim Fong; Eng Hwa Wong
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)