Can I read MicroRNA Targeted Cancer Therapy on EtoBox?

MicroRNA Targeted Cancer Therapy by Fazlul H. Sarkar (eds.) is a nonfiction available to read on EtoBox.

What is MicroRNA Targeted Cancer Therapy about?

Since the discovery of microRNAs (miRNAs) some twenty years ago by Victor Ambros, David Baulcombe and Gary Ruvkun, these three scientists worked to uncover the mystery of miRNA, the small segments of nucleotides that silence genes. While studying the development of the nematode worm, Ambros and Ruvkun discovered miRNA in animals, while Baulcombe discovered it in plants. Since their discovery, it took more than two decade to fully appreciate the value of miRNA in human health and diseases. Emerging evidence suggest that the activation of oncogenes and/or the inactivation of tumor suppressor genes contribute to the development and progression of tumors. The regulation of genes is by far controlled by many transcription factors which are often deregulated during the development and progression of cancer. In addition, emerging evidence clearly suggests that the deregulation of miRNAs or small non-coding RNAs could also regulate the expression of genes and likewise, miRNA genes are also regulated by transcription factors. The most attractive feature of miRNAs is that one miRNA can regulate many target genes (mRNAs) and thus miRNA targeted therapy is highly promising because multiple gen

Who reads MicroRNA Targeted Cancer Therapy?

Author

Fazlul H. Sarkar (eds.)

Publisher

Springer International Publishing

Published

2014

Language

EN

ISBN

9783319051338

Category

nonfiction

Subjects

Medical, Science, Medicine