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This document describes a new spectrophotometric method for determining concentrations of three cephalosporin drugs (cefixime, cephalexine, and cefotaxime) in pharmaceutical formulations. The method involves derivatizing the cephalosporins with 1,2-naphthoquinone-4-sulfonic acid, which allows for spectrophotometric analysis. Optimal reaction conditions were determined, and the method was found to be accurate, precise, and capable of determining drug concentrations within specified ranges with good recovery

Author

nur azizah

Language

EN