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Risk Profile of Patients with Spontaneous Cervical Artery Dissection by Elisabetta Del Zotto; Mario Grassi; Marialuisa Zedde; Andrea Zini; Anna Bersano; Carlo Gandolfo; Giorgio Silvestrelli; Claudio Baracchini; Paolo Cerrato; Corrado Lodigiani; Simona Marcheselli; Maurizio Paciaroni; Alessandra Spalloni; Manuel Cappellari; Massimo Del Sette; Anna Cavallini; Enrico Maria Lotti; Maria Luisa Delodovici; Mauro Gentile; Mauro Magoni; Marina Padroni; Cristiano Azzini; Maria Vittoria Calloni; Elisa Giorli; Massimiliano Braga; Paolo La Spina; Fabio Melis; Rossana Tassi; Valeria Terruso; Rocco Salvatore Calabrò; Valeria Piras; Alessia Giossi; Sandro Sanguigni; Carla Zanferrari; Marina Mannino; Irene Colombo; Carlo Dallocchio; Patrizia Nencini; Valeria Bignamini; Alessandro Adami; Rita Bella; Rosario Pascarella; Zafer Keser; Alessandro Pezzini; the Italian Project on Stroke in Young Adults—Cervical Artery Dissection, (IPSYS CeAD) Research Group is a Medicine article available to read on EtoBox.

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## Objective Epidemiological data to characterize the individual risk profile of patients with spontaneous cervical artery dissection (sCeAD) are rather inconsistent. ## Methods and Results In the setting of the Italian Project on Stroke in Young Adults Cervical Artery Dissection (IPSYS CeAD), we compared the characteristics of 1,468 patients with sCeAD (mean age = 47.3 ± 11.3 years, men = 56.7%) prospectively recruited at 39 Italian centers with those of 2 control groups, composed of (1) patients whose ischemic stroke was caused by mechanisms other than dissection (non‐CeAD IS) selected from the prospective IPSYS registry and Brescia Stroke Registry and (2) stroke‐free individuals selected from the staff members of participating hospitals, matched 1:1:1 by sex, age, and race. Compared to stroke‐free subjects, patients with sCeAD were more likely to be hypertensive (odds ratio [OR] = 1.65, 95% confidence interval [CI] = 1.37–1.98), to have personal history of migraine with aura (OR = 2.45, 95% CI = 1.74–3.34), without aura (OR = 2.67, 95% CI = 2.15–3.32), and family history of vascular disease in first‐degree relatives (OR = 1.69, 95% CI = 1.39–2.05), and less likely to be diabetic

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Author

Elisabetta Del Zotto; Mario Grassi; Marialuisa Zedde; Andrea Zini; Anna Bersano; Carlo Gandolfo; Giorgio Silvestrelli; Claudio Baracchini; Paolo Cerrato; Corrado Lodigiani; Simona Marcheselli; Maurizio Paciaroni; Alessandra Spalloni; Manuel Cappellari; Massimo Del Sette; Anna Cavallini; Enrico Maria Lotti; Maria Luisa Delodovici; Mauro Gentile; Mauro Magoni; Marina Padroni; Cristiano Azzini; Maria Vittoria Calloni; Elisa Giorli; Massimiliano Braga; Paolo La Spina; Fabio Melis; Rossana Tassi; Valeria Terruso; Rocco Salvatore Calabrò; Valeria Piras; Alessia Giossi; Sandro Sanguigni; Carla Zanferrari; Marina Mannino; Irene Colombo; Carlo Dallocchio; Patrizia Nencini; Valeria Bignamini; Alessandro Adami; Rita Bella; Rosario Pascarella; Zafer Keser; Alessandro Pezzini; the Italian Project on Stroke in Young Adults—Cervical Artery Dissection, (IPSYS CeAD) Research Group

Publisher

Wiley

Published

2023

Language

EN

Field

Medicine (Health Sciences)