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SHMT1 C1420T and Neural Tube Defects by Prasoona Konda is a document available to read on EtoBox.

The study investigates the association between the SHMT1 C1420T genetic variant and the risk of neural tube defects (NTDs) in fetuses, using case-control and family-based triad approaches. Results indicate that the paternal TT genotype combined with the maternal CT genotype significantly increases the risk of NTDs, particularly spina bifida, and shows a notable maternal transmission bias of the variant allele to affected offspring. This research highlights the importance of parental genotype compatibility i

Author

Prasoona Konda

Language

EN