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This study focuses on the design, synthesis, and evaluation of triazole-linked chalcone and dienone hybrid compounds for their antimalarial activity against Plasmodium falciparum. The research highlights the use of a Cu(I)-catalyzed cycloaddition method to create these hybrids, with compound 8b showing significant antimalarial potency. The findings suggest that molecular hybridization could be a promising strategy in developing new antimalarial agents, particularly in the context of rising drug resistance.

Author

Priya yu

Language

EN